Your Daily CRISPR & Gene Editing Briefing

FDA Approves First Gene Therapy for Young Children with Sickle Cell Disease

• Researchers have developed a new genetic screening method that allows for the efficient and uniform modulation of individual genes across entire tissues in organoids, providing novel insights into human development. Published on July 9, 2026, this streamlined CRISPR approach overcomes previous limitations of mosaic-like gene knockdown, enabling a more comprehensive study of tissue-wide structural development.

  News Medical

• In a significant shift from the long-standing paradigm, engineers at the University of Florida have developed a new CRISPR technology that uses DNA, rather than RNA, to guide CRISPR enzymes to their targets. This DNA-guided system, formally published in *Nature Biotechnology* on May 15, 2026, promises safer, more precise, and more affordable diagnostics and treatments, as DNA guides are more stable and easier to manufacture than their RNA counterparts.

  News Medical